TV Blog
Tv is our narcotic

Archive for the ‘cancer’ Category

Effect of Methimazole Treatment on Doxorubicin-induced Cardiotoxicity

 

 

Effect of methimazole treatment on doxorubicin-induced cardiotoxicity

   Abdel-Moneim M.Osman Ph.D.,  Marwa M.Nemnem  M.Pharm.Sc.,Amany A.Emam,Ph.D.Wael T.Abou daif and Mohamed T.Khayyal  Ph.D.

 

 aAuthor for correspondence: Abdel-Moneim M.Osman, Pharmacology Dept.,College of Medicine, KAAU, Jeddah,P.O.box 80202, Saudi Arabia( Fax +96626408404, e.mail. moneimosman@hotmail.com

 Key Words : Methimazole, Doxorubicin, cardiotoxicity, interaction

Running title: Protective effect of methimazole

 

 

 

1. Introduction

 

Doxorubicin is the most widely used drugs in the treatment of a variety of human neoplasm (1,7).Unfortunately with increasing the use of doxorubicin, acute as well as chronic cumulative dose-dependent cardiomyopathy have been recognized as the major limiting factor of doxorubicin chemotherapy (21, 6).

Several mechanisms for the doxorubicin-induced cardio toxicity have been proposed, including membrane lipid per oxidation, Read the rest of this entry »

No Comments

Bone Cancer: Causes, Symptoms, Diagnosis, Treatment and Prognosis

Bone cancer is rare and accounts for less than 1% of all new tumors. Not all bone tumors are fatal in fact benign (non cancerous) abnormalities are more common than malignant ones. Most bone cancers are secondary and have been spread from another site. Primary bone cancer which starts in the bone is quite rare constituting less than one per cent of all malignant tumors. They are more common in males, especially in children and adolescents. The most common type of primary bone cancer is osteosarcoma. This type of carcinoma usually affects young adults. It can affect any bone, but the arms, legs and pelvis are more commonly affected. Other less common forms of primary bone cancer include Ewing sarcoma, Read the rest of this entry »

No Comments

The Minneapolis Urban League Receives National Attention and Unveils Collaborative Logo!

Breaking news the Minneapolis Urban League has gain national attention for their upcoming 1st Annual Minneapolis Urban League Prostate Cancer Awareness and Education Day on June 20, 2008.

Stephanie Chisolm, PhD – Director of Patient Education with the American Urological Association in Maryland says, “This is a great opportunity for the AMA to engage with the Minneapolis Urban League and their Social Wellness Cluster that does such a great job in the Twin Cities.”   Mr. Theodus Mitchell with the Center for Disease Control (CDC) says, “This is great and the CDC supports any efforts that the Minneapolis Urban League is involved in to address health disparities in communities of color.”

Mr. James Hedley with the National Read the rest of this entry »

No Comments